Ly 3200882
Webly3200882 は、38.2 nm の ic50 を持つ、強力で高度に選択的な atp 競合性および経口活性 tgf-β 受容体 1 (alk5) 阻害剤です。 WebApplication In Synthesis of [ 1898283-02-7 ] * All experimental methods are cited from the reference, please refer to the original source for details.We do not guarantee the accuracy of the content in the reference. Downstream synthetic route of [ 1898283-02-7 ]
Ly 3200882
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Web1 iul. 2024 · Abstract. The transforming growth factor β (TGFβ) signaling pathway is a pleiotropic cellular pathway that plays a critical role in cancer. In fact, aggressive tumors … WebLY-3200882 is an inhibitor of TGFβR1. The TGF-β pathway is frequently deregulated in tumors, and plays an important role in the regulation of cell growth, differentiation, and apopsosis. Preliminary safety and efficacy studies suggest that LY-3200882 is for patients with certain advanced or metastatic cancers, for example it inhibits tumor ...
Web产品描述. LY 3200882 (LY3200882) 是一种 ATP 竞争性和可口服的 TGFβRI (ALK5) 选择性抑制剂， IC 50 为 38.2 nM ，是一种免疫调节剂；可抑制多种原致癌基因的活性，在多 … WebLY 3200882 is a potent, highly selective inhibitor of TGF-β receptor type 1 (TGFβRI). It potently inhibits TGFβ mediated SMAD phosphorylation in vitro in tumor and immune cells and in vivo in subcutaneous tumors in a dose dependent fashion.
WebLY3200882 related products. MedChemExpress provides thousands of inhibitors, modulators and agonists with high purity and quality, excellent customer reviews, precise …
WebLY-3200882 is one of numerous organic compounds composing American Elements's comprehensive catalog of life science products. American Elements supplies life science materials in most volumes including bulk quantities and also can produce materials to customer specifications. Most materials can be produced in high and ultra high purity …
WebLY-3200882 is a next generation small molecule inhibitor of TGF-β receptor type 1 (TGFβRI) and a promising immune modulatory agent. It is a potent, highly selective inhibitor of TGFβRI embodied in a structural platform with a synthetically scalable route, in an ATP competitive fashion to the serine-threonine kinase domain of TGFβRI. red flower from hawaiiWebChemicalBook 致力于为化学行业用户提供LY-3200882的性质、化学式、分子式、比重、密度,同时也包括LY-3200882的沸点、熔点、MSDS、用途、作用、毒性、价格、生产厂家 … knorr cream of leek soup mixWebLY3200882 1898283-02-7 LY 3200882 LY-3200882 TGF-β Receptor Transforming growth factor beta receptors Anti-cancer ATP-competitive TGFβRI serine-threonine SMAD … knorr creamy bruschetta chickenWebLY 3200882 Alternative Names: LY-3200882 Latest Information Update: 28 Dec 2024. Price : $50 * Buy Profile. Adis is an information provider. We do not sell or distribute actual … red flower girl dresses australiaWebApplication In Synthesis of [ 1898283-02-7 ] * All experimental methods are cited from the reference, please refer to the original source for details.We do not guarantee the … knorr creme fraiche sauce kaufenWeb5 aug. 2024 · LY-3200882 . LY-3200882 is under investigation in clinical trial NCT04158700 (A Study of LY3200882 and Pembrolizumab in Participants With Advanced Cancer). LY … knorr cremesuppenWebLY-3200882 is an orally active TGFbeta inhibitor. LY3200882 targets transforming growth factor-beta (TGFb), with potential antineoplastic activity. Upon administration, … knorr cream of seafood soup