WebPolyclonal Antibody for studying EIF2S1/eIF2-alpha (Ser52) phosphate. Cited in 930 publications. Validated for Western Blotting, Simple Western™. Available in 2 sizes. Highly specific and rigorously validated in-house, … The protein encoded by this gene is the alpha (α) subunit of the translation initiation factor eIF2 protein complex which catalyzes an early regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA (Met-tRNAi ) to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, eIF2, and GTP. eIF2 is composed of 3 nonidentical subunits, alpha (α, 36 kD, this article), beta (β, 38 kD), and gamma (γ, 52 kD). The rate of formation of the ternary co…
Anti-EIF2S1 (phospho S51) antibody (ab131505) Abcam
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EIF2S1 Gene - GeneCards IF2A Protein IF2A Antibody
WebEIF2S1 Antibody (AHO0802) in ICC/IF. Immunofluorescence analysis of eIF2a was done on 70% confluent log phase A549 cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with … WebImmunocytochemistry analysis of Phospho-EIF2S1 (Ser51, Ser52) in HepG2 cells (4hrs of LPS treatment). Samples were treated with PFA, permeabilized in 0.1% Triton X-100, blocked in 10% serum (45 min at 25°C), and incubated with polyclonal antibody ( Product # PA5-114570) at a dilution of 1:200 (1 hr at 37°C). Secondary staining was applied ... WebJun 19, 2024 · Different intrinsic and extrinsic stress pathways including endoplasmic reticulum (ER) stress converge on the phosphorylation of eukaryotic translation initiation factor 2A (EIF2A, best known as eIF2α), which characterizes the so-called "integrated stress response". This phosphorylation event is imp … homestead protection in colorado